Peptide Database

Peptide NameTH peptide

Function Ontology

Anticancer

Antimicrobial

Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide

Delivery / Targeting ▸ Drug delivery vehicle

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC107H163N33O23

DescriptionStandard

        AGYLLGHINLHHLAHLHHIL
    

Molecular Weight2279.65 Da

Isoelectric Point (pI)7.24

Net Charge (pH 7.0)0.32

Net Charge (pH 7.4) -0.17

Charge Density (pH 7.0) 0.0159

GRAVY Index0.53

Hydrophobic Moment 0.30

Boman Index0.42

Instability Index54.58

Aliphatic Index 166.00

Aromaticity 0.0500

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 851.62

LogP -3.10

H-bond Donors 29.0

H-bond Acceptors 29.0

Rotatable Bonds 71.0

Heavy Atoms 163.0

Ring Count 7.0

Amide Bonds 20.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0038182 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermNone

C-TermAmidation

Other Modsα-aminoisobutyric acid (Aib) residue between L16 and H17

Bio-Activity Profile

Function

Antimicrobial Anticancer Hemolytic Cell-penetrating peptide pH-responsive tumor targeting

TargetC26 tumor cells; tumor spheroids

Methodcellular uptake / tumor spheroid uptake assay

RECORD: Rec_0289063 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermNone

C-TermAmidation

Other Modsα-aminoisobutyric acid (Aib) residue between L16 and H17

Bio-Activity Profile

Function

Cell-penetrating peptide Cargo delivery pH-responsive tumor targeting

TargetC26 tumor cells; tumor spheroids

Methodcellular uptake / tumor spheroid uptake assay

RECORD: Rec_0351113 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermNone

C-TermAmidation

Other Modsα-aminoisobutyric acid (Aib) residue between L16 and H17

Bio-Activity Profile

Function

Antimicrobial Anticancer Cytotoxic Cell-penetrating peptide pH-responsive tumor targeting

TargetC26 tumor cells; tumor spheroids

Methodcellular uptake / tumor spheroid uptake assay