Peptide Database

Peptide NameNEC1_NICLS

Function Ontology

Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Neurological / Signaling ▸ Signaling peptide

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Standard StatusStandard

Sequence Length229 amino acids

Chemical FormulaC1114H1750N286O324S9

DescriptionStandard

        KGEVFVFPRGLVHFQKNNGEVPAAVISAFNSQLPGTQSIPITLFGASPPVKVNGFPCKTNFTAADFSSLAISKPGATNNKFGSVVTTANVEQVPGLNTLGMAAFGINSKIFQSMEMAILFLLAISIDRYCFAADEDMLQDVCVADLHSKVPDDVLAQTFQINTEDVQQIKSKFAPVKKFVSLARIDYAPGGINPPHTHPRASEMVFVMEGELDVGFITTANVLVSKKII
    

Molecular Weight24622.12 Da

Isoelectric Point (pI)6.09

Net Charge (pH 7.0)-1.90

Net Charge (pH 7.4) -2.39

Charge Density (pH 7.0) -0.0083

GRAVY Index0.19

Hydrophobic Moment 0.60

Boman Index0.18

Instability Index24.36

Aliphatic Index 91.53

Aromaticity 0.0873

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3105.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0195786 VERIFIED: YES

Provenance & Taxonomy

OrganismNicotiana langsdorffii x Nicotiana sanderae [Plant]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Signaling Enzyme inhibitory ACE inhibitory Antihypertensive

TargetAngiotensin-converting enzyme