Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC539H871N147O164S3

DescriptionStandard

        PDLAGHEKFGLGNVKYNISRIHVTAVELPSASISLLPGSGIKLVIGNASLTIDMNWSIRTWMFKDSGRGTVHISKVFVTAIFSTPLDNTGPTSISLSSCRTTSGDVDIKLNGKT
    

Molecular Weight12130.76 Da

Isoelectric Point (pI)9.33

Net Charge (pH 7.0)3.21

Net Charge (pH 7.4) 2.97

Charge Density (pH 7.0) 0.0282

GRAVY Index0.07

Hydrophobic Moment 0.54

Boman Index0.13

Instability Index15.51

Aliphatic Index 96.58

Aromaticity 0.0614

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4952.98

LogP -56.55

H-bond Donors 177.0

H-bond Acceptors 173.0

Rotatable Bonds 400.0

Heavy Atoms 853.0

Ring Count 17.0

Amide Bonds 119.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0351894 VERIFIED: NO

Provenance & Taxonomy

OrganismCettia cetti [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria