Peptide Database

Peptide NameEsculentin-2-AJ1 antimicrobial peptide

Function Ontology

Antimicrobial

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length76 amino acids

Chemical FormulaC377H617N97O109S6

DescriptionStandard

        MFTLKKSMLLLFFLGTISLSFCEEERSADEVDGEKEVKRGIFSIIKTAAKFLGKNLLKEAGKAGMEHLACKAKNEC
    

Molecular Weight8444.91 Da

Isoelectric Point (pI)8.49

Net Charge (pH 7.0)1.57

Net Charge (pH 7.4) 1.23

Charge Density (pH 7.0) 0.0207

GRAVY Index-0.03

Hydrophobic Moment 0.70

Boman Index0.03

Instability Index25.69

Aliphatic Index 88.68

Aromaticity 0.0789

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3342.84

LogP -27.35

H-bond Donors 119.0

H-bond Acceptors 118.0

Rotatable Bonds 302.0

Heavy Atoms 589.0

Ring Count 7.0

Amide Bonds 77.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0203918 VERIFIED: YES

Provenance & Taxonomy

OrganismAmolops [Animal]

Tax ID109940

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Amphibian defense peptide Antimicrobial Non-hemolytic Non-ribosomal

RECORD: Rec_0212194 VERIFIED: YES

Provenance & Taxonomy

OrganismAmolops jingdongensis [Animal]

FamilyEsculentin

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial