Peptide Database

Peptide NameLysenin (Beta-barrel pore-forming toxin) (Beta-PFT) (Invertebrate cytolysin pore) (efL1)

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length297 amino acids

Chemical FormulaC1490H2313N395O462S9

DescriptionStandard

        MSAKAAEGYEQIEVDVVAVWKEGYVYENRGSTSVDQKITITKGMKNVNSETRTVTATHSIGSTISTGDAFEIGSVEVSYSHSHEESQVSMTETEVYESKVIEHTITIPPTSKFTRWQLNADVGGADIEYMYLIDEVTPIGGTQSIPQVITSRAKIIVGRQIILGKTEIRIKHAERKEYMTVVSRKSWPAATLGHSKLFKFVLYEDWGGFRIKTLNTMYSGYEYAYSSDQGGIYFDQGTDNPKQRWAINKSLPLRHGDVVTFMNKYFTRSGLCYDDGPATNVYCLDKREDKWILEVVG
    

Molecular Weight33440.26 Da

Isoelectric Point (pI)5.86

Net Charge (pH 7.0)-4.86

Net Charge (pH 7.4) -5.57

Charge Density (pH 7.0) -0.0164

GRAVY Index-0.41

Hydrophobic Moment 0.57

Boman Index0.00

Instability Index37.48

Aliphatic Index 76.73

Aromaticity 0.1044

Extinction Coeff. Reduced 58330.00

Extinction Coeff. Oxidized 58455.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0378093 VERIFIED: YES

Provenance & Taxonomy

OrganismEisenia fetida [Animal]

FamilyLysenin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antiparasitic Cytolytic Toxin Cytotoxic Hemolytic

TargetNo Target Organism Found