Peptide Database

Peptide NameEndolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length151 amino acids

Chemical FormulaC746H1165N233O220S6

DescriptionStandard

        MSRVQFKQREATNAIFVHCSATKATQDVGVREIRQWHKEQGWLDVGYHFIIRRDGTVEDGRDVNAVGSHARGHNHNSVGVCLVGGIDEKGRHEANFTPQQMSSLRTLLEVLMDKYPSAVLKAHHDVAPKACPSFDLQRWWKHNELVTSDRG
    

Molecular Weight17110.05 Da

Isoelectric Point (pI)8.51

Net Charge (pH 7.0)2.37

Net Charge (pH 7.4) 1.57

Charge Density (pH 7.0) 0.0157

GRAVY Index-0.61

Hydrophobic Moment 0.75

Boman Index-0.11

Instability Index49.52

Aliphatic Index 72.25

Aromaticity 0.0728

Extinction Coeff. Reduced 24980.00

Extinction Coeff. Oxidized 25105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7332.88

LogP -79.03

H-bond Donors 259.0

H-bond Acceptors 238.0

Rotatable Bonds 570.0

Heavy Atoms 1205.0

Ring Count 29.0

Amide Bonds 164.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0185076 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia phage Ebrios [Virus]

FamilyN-acetylmuramoyl-L-alanine amidase 2

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Hydrolase Cytolytic Non-hemolytic