Peptide Database

Peptide NameEsculentin-2-a02

Function Ontology

Antimicrobial

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length80 amino acids

Chemical FormulaC400H650N102O119S5

DescriptionStandard

        MFTMKKPILVLFFLGTISLSLCEQERSADEDDGEEIKEEEVKRGIFSLFKTAAKFVGKNLLKEAGKAGLEHLACKVKNEC
    

Molecular Weight8952.38 Da

Isoelectric Point (pI)5.84

Net Charge (pH 7.0)-1.42

Net Charge (pH 7.4) -1.77

Charge Density (pH 7.0) -0.0177

GRAVY Index-0.15

Hydrophobic Moment 0.67

Boman Index0.00

Instability Index38.65

Aliphatic Index 90.25

Aromaticity 0.0750

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3585.21

LogP -28.89

H-bond Donors 125.0

H-bond Acceptors 124.0

Rotatable Bonds 318.0

Heavy Atoms 626.0

Ring Count 8.0

Amide Bonds 82.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0105838 VERIFIED: YES

Provenance & Taxonomy

OrganismAmolops [Animal]

Tax ID109940

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Amphibian defense peptide Antimicrobial Non-hemolytic Non-ribosomal

RECORD: Rec_0351910 VERIFIED: NO

Provenance & Taxonomy

OrganismAmolops jingdongensis [Animal]

FamilyEsculentin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial