Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length87 amino acids

Chemical FormulaC455H713N133O127S11

DescriptionStandard

        MTICRKRFEKLYSEKHNFSTIFEKAKYGTKKNNPARSKEQYAVFNWWEACIKLSGQCKNRCGEKEFKMSYCARPTTLCCMRHCDRIE
    

Molecular Weight10431.06 Da

Isoelectric Point (pI)9.41

Net Charge (pH 7.0)9.61

Net Charge (pH 7.4) 9.13

Charge Density (pH 7.0) 0.1104

GRAVY Index-0.89

Hydrophobic Moment 0.52

Boman Index-0.26

Instability Index45.53

Aliphatic Index 40.46

Aromaticity 0.1264

Extinction Coeff. Reduced 16960.00

Extinction Coeff. Oxidized 17460.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4303.37

LogP -42.28

H-bond Donors 161.0

H-bond Acceptors 150.0

Rotatable Bonds 357.0

Heavy Atoms 726.0

Ring Count 17.0

Amide Bonds 93.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0309040 VERIFIED: NO

Provenance & Taxonomy

OrganismUrsus arctos horribilis [Bacterium]

FamilyDefensin

Tax ID116960

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence