Peptide Database

Peptide NameColicin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length191 amino acids

Chemical FormulaC912H1450N272O288S

DescriptionStandard

        ERQHIAVVAGVPASIPVVDAKPTTHPGVFSVSVPGLPDLQVSTVKNAPAMTALPRGVTDEKDRTVHPAGFTFGGSSHEAVIRFPKESGQAPVYVSVTDVLTPEQVKQRQDEENRRQQEWDATHPVEVAERNYRLASDELNRANVDVAGKQERQIQAAQAVAARKGELDAANKTFADAKEEIKKFERFAHDP
    

Molecular Weight20864.98 Da

Isoelectric Point (pI)5.90

Net Charge (pH 7.0)-3.60

Net Charge (pH 7.4) -4.12

Charge Density (pH 7.0) -0.0188

GRAVY Index-0.60

Hydrophobic Moment 0.75

Boman Index-0.10

Instability Index41.77

Aliphatic Index 72.51

Aromaticity 0.0524

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 9013.13

LogP -114.94

H-bond Donors 303.0

H-bond Acceptors 291.0

Rotatable Bonds 685.0

Heavy Atoms 1473.0

Ring Count 31.0

Amide Bonds 208.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0388158 VERIFIED: YES

Provenance & Taxonomy

OrganismSalmonella enterica subsp. enterica serovar Gaminara [Bacterium]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

TargetEscherichia coli (Gram-negative)