Peptide Database

Peptide NameParathyroid hormone

Function Ontology

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length88 amino acids

Chemical FormulaC452H745N143O133S4

DescriptionStandard

        SVSEMQLMHNLGEHRHTVERQDWLQMKLQDVHSALEDARTQRPRNKEDIVLGEIRNRRLLPEHLRAAVQKKSIDLDKAYMNVLFKTKP
    

Molecular Weight10438.89 Da

Isoelectric Point (pI)9.52

Net Charge (pH 7.0)2.91

Net Charge (pH 7.4) 2.43

Charge Density (pH 7.0) 0.0331

GRAVY Index-0.88

Hydrophobic Moment 0.68

Boman Index-0.27

Instability Index58.63

Aliphatic Index 87.50

Aromaticity 0.0341

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4544.72

LogP -43.83

H-bond Donors 157.0

H-bond Acceptors 145.0

Rotatable Bonds 364.0

Heavy Atoms 732.0

Ring Count 12.0

Amide Bonds 97.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0197300 VERIFIED: YES

Provenance & Taxonomy

OrganismGallus gallus [Animal]

FamilyParathyroid hormone

Tax ID9031

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Metabolic regulation Physiological regulation Growth regulation Development regulation Receptor modulation ACE inhibitory

Half-LifeMammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour