Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length78 amino acids

Chemical FormulaC358H572N96O105S14

DescriptionStandard

        MKSFTVAVTAAIMLTFICLQQSSAVPLPEVTASSPPPDLFSTCLTQMPYTIRQQREARGCRFCCGCCGMSGCGVCCPF
    

Molecular Weight8349.86 Da

Isoelectric Point (pI)8.07

Net Charge (pH 7.0)1.41

Net Charge (pH 7.4) 1.04

Charge Density (pH 7.0) 0.0180

GRAVY Index0.46

Hydrophobic Moment 0.45

Boman Index0.17

Instability Index66.21

Aliphatic Index 66.28

Aromaticity 0.0769

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 2115.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3146.91

LogP -36.01

H-bond Donors 118.0

H-bond Acceptors 121.0

Rotatable Bonds 260.0

Heavy Atoms 573.0

Ring Count 13.0

Amide Bonds 82.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0151233 VERIFIED: NO

Provenance & Taxonomy

OrganismNothobranchius furzeri [Animal]

FamilyHepcidin

Tax ID105023

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal