Peptide Database

Peptide NameAs Cathelicidin 6, As-CATH6

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length26 amino acids

Chemical FormulaC139H219N47O31

DescriptionStandard

        TRWLWLLRGGLKAAGWGIRAHLNRNQ
    

Molecular Weight3044.52 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)4.48

Net Charge (pH 7.4) 4.24

Charge Density (pH 7.0) 0.1725

GRAVY Index-0.45

Hydrophobic Moment 0.53

Boman Index-0.06

Instability Index51.94

Aliphatic Index 101.54

Aromaticity 0.1154

Extinction Coeff. Reduced 16500.00

Extinction Coeff. Oxidized 16500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1289.99

LogP -9.90

H-bond Donors 48.0

H-bond Acceptors 37.0

Rotatable Bonds 99.0

Heavy Atoms 217.0

Ring Count 7.0

Amide Bonds 28.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0365422 VERIFIED: YES

Provenance & Taxonomy

OrganismAlligator sinensis [Animal]

Familycathelicidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal

TargetVibrio cholerae

Activity37.5 μg/mL

MethodMIC

RECORD: Rec_0392026 VERIFIED: YES