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MYP_001070
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Basic Information
As Cathelicidin 6, As-CATH6
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
26 amino acids
C139H219N47O31
Standard
Sequence
TRWLWLLRGGLKAAGWGIRAHLNRNQ
Physicochemical Analysis
3044.52 Da
12.00
4.48
4.24
0.1725
-0.45
0.53
-0.06
51.94
101.54
0.1154
16500.00
16500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1289.99
-9.90
48.0
37.0
99.0
217.0
7.0
28.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0118670 VERIFIED: YES
Provenance & Taxonomy
Alligator sinensis [Animal]
cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus
37.5 μg/mL
MIC
PMID28798159 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28798159/
RECORD: Rec_0132879 VERIFIED: YES
Provenance & Taxonomy
Alligator sinensis [Animal]
cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Human gastric cancer BGC-823
200 μg/mL
PMID28798159 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28798159/
RECORD: Rec_0149271 VERIFIED: YES
Provenance & Taxonomy
Alligator sinensis [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-negative
Escherichia coli
1.54 μM
MIC
RECORD: Rec_0157106 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Anticancer
RECORD: Rec_0164374 VERIFIED: YES
Provenance & Taxonomy
Alligator sinensis [Animal]
cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Stenotrophomonas maltophilia 2
18.75 μg/mL
MIC
PMID28798159 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28798159/
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