Peptide Database

Peptide NameBactericidal permeability-increasing protein

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length283 amino acids

Chemical FormulaC1409H2198N372O399S9

DescriptionStandard

        RHHGSFNLNVEHIYIKTILKLGRDDSGKPTVDISACSTSISNVRVHFSGKLSWLYNLFRRTIESKFKKSLEKKLCDTLRSSARRYLQPYLQTVPVTANIDAVAGIDYSLTAAPVATAKFLNVGLKGECFSLAQRTPVPFTPPALAVPPVHNRMVYFGVSSYFFNTASFAYHTAGALIFDITDAMIPEDIEFRLNTSTFAAFLPQLDEMYPNMPMKFRLSAPSAPFLNIGTNGVSLQPVVDIQAYAIYPNGNLAPLFLLGLTGNVSATTDVQSGRMVGSLAVGR
    

Molecular Weight31021.36 Da

Isoelectric Point (pI)9.32

Net Charge (pH 7.0)7.26

Net Charge (pH 7.4) 6.66

Charge Density (pH 7.0) 0.0257

GRAVY Index0.08

Hydrophobic Moment 0.75

Boman Index0.13

Instability Index47.12

Aliphatic Index 91.34

Aromaticity 0.1060

Extinction Coeff. Reduced 21890.00

Extinction Coeff. Oxidized 22015.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0239531 VERIFIED: NO

Provenance & Taxonomy

OrganismAnas platyrhynchos [Animal]

FamilyBPI/LBP

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic Non-ribosomal

TargetGram-negative bacteria

MethodQualitative functional evidence