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MYP_001054
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Basic Information
A12L (V13KL peptide derivative)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
26 amino acids
C142H236N36O34
Standard
Sequence
KWKSFLKTFKSLKKTVLHTALKAISS
Physicochemical Analysis
2991.61 Da
10.78
6.84
6.58
0.2631
-0.14
0.69
-0.02
3.29
93.85
0.1154
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1159.04
-8.37
43.0
42.0
105.0
212.0
5.0
25.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0069593 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Pseudomonas aeruginosa PAO1
15.6 μg/mL
MIC
PMID17158938 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17158938/
RECORD: Rec_0085923 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Pseudomonas aeruginosa PAO1
15.6 μg/mL
MIC
PMID17158938 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17158938/
RECORD: Rec_0087193 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Designed peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PMID21252288 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21252288/
RECORD: Rec_0088734 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative Hemolytic
human red blood cells
PMID17158938 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17158938/
RECORD: Rec_0108384 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Pseudomonas aeruginosa CP204
15.6 μg/mL
MIC
PMID17158938 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17158938/
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