Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length61 amino acids

Chemical FormulaC305H509N79O84S8

DescriptionStandard

        MKLILVVLTITLLLVQVTQAMYCWGKLGRCKTTCEQNEVFHILCTDEAKCCVNPKNVPVKT
    

Molecular Weight6883.30 Da

Isoelectric Point (pI)8.61

Net Charge (pH 7.0)2.53

Net Charge (pH 7.4) 2.16

Charge Density (pH 7.0) 0.0415

GRAVY Index0.42

Hydrophobic Moment 0.56

Boman Index0.14

Instability Index34.01

Aliphatic Index 111.64

Aromaticity 0.0492

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2623.81

LogP -20.28

H-bond Donors 95.0

H-bond Acceptors 96.0

Rotatable Bonds 230.0

Heavy Atoms 476.0

Ring Count 7.0

Amide Bonds 66.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0100171 VERIFIED: NO

Provenance & Taxonomy

OrganismLeptonychotes weddellii [Animal]

FamilyDefensin

Tax ID9713

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence

RECORD: Rec_0391363 VERIFIED: NO