Peptide Database

Peptide Namemt_T18S/L22 W/P27A

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length12 amino acids

Chemical FormulaC72H99N15O21

DescriptionStandard

        ESFSDWWKLLAE
    

Molecular Weight1510.64 Da

Isoelectric Point (pI)4.43

Net Charge (pH 7.0)-2.15

Net Charge (pH 7.4) -2.33

Charge Density (pH 7.0) -0.1796

GRAVY Index-0.47

Hydrophobic Moment 0.53

Boman Index0.11

Instability Index18.14

Aliphatic Index 73.33

Aromaticity 0.2500

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 593.38

LogP -2.15

H-bond Donors 21.0

H-bond Acceptors 19.0

Rotatable Bonds 47.0

Heavy Atoms 108.0

Ring Count 5.0

Amide Bonds 11.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0344002 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Familyp53-derived peptide

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Anticancer

TargetMCF-7

Activity27.0 μM

MethodIC50

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