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MYP_001008
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Basic Information
LysAB2 P3
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
33 amino acids
C172H285N51O42S
Standard
Sequence
NPEKALEKLIAIQKAIKGMLNGWFTGVGFRRKR
Physicochemical Analysis
3771.48 Da
11.12
5.76
5.55
0.1746
-0.40
0.63
-0.09
27.65
88.79
0.0909
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1541.42
-11.54
54.0
49.0
132.0
266.0
5.0
35.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0337527 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Clinically isolated colistin-resistant MDRAB M2925
8 μM
MIC
PMID28904355 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28904355/
RECORD: Rec_0390930 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Colistin-susceptible MDRAB M3237
16 μM
MIC
PMID28904355 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28904355/
RECORD: Rec_0407934 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
A549 (Not active up to 200 μm)
PaperPubMed PMID: 28904355 PMID28904355 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28904355/
RECORD: Rec_0412492 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC 25923
128 μM
MIC
PMID28904355 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28904355/
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