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MYP_000994
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Basic Information
Psacotheasin
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
34 amino acids
C143H220N46O44S6
Standard
Sequence
CIAKGNGCQPSGVQGNCCSGHCHKEPGWVAGYCK
Physicochemical Analysis
3479.95 Da
8.33
1.87
1.47
0.0551
-0.41
0.19
0.04
26.91
34.41
0.0588
6990.00
7365.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1427.60
-20.07
53.0
54.0
110.0
239.0
7.0
37.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0129193 VERIFIED: YES
Provenance & Taxonomy
Psacothea hilaris [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Staphylococcus aureus ATCC 25923
25 μM
MIC
PaperIsolation and Characterization of Psacotheasin, a Novel Knottin-Type Antimicrobial Peptide, from Psacothea hilaris
RECORD: Rec_0175741 VERIFIED: YES
Provenance & Taxonomy
Psacothea hilaris [Animal]
Gurmarin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC 25923
25 μM
MIC
PMID20467242 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20467242/
RECORD: Rec_0183906 VERIFIED: YES
Provenance & Taxonomy
Psacothea hilaris [Animal]
Psacotheasin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Gram-positive bacterial strains; Gram-negative bacterial strains
Qualitative antimicrobial activity evidence
PaperJ Microbiol Biotechnol. 2010 Apr;20(4):708-11 | http://www.ncbi.nlm.nih.gov/pubmed/20467242 PMID20467242 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20467242/
RECORD: Rec_0207573 VERIFIED: YES
Provenance & Taxonomy
Psacothea hilaris [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Enterococcus faecium ATCC 29212
25 μM
MIC
PaperIsolation and Characterization of Psacotheasin, a Novel Knottin-Type Antimicrobial Peptide, from Psacothea hilaris
RECORD: Rec_0217569 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 14.7%, T 47.1%, C 38.2% [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Toxic Antimicrobial Antifungal Hemolytic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
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