Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length111 amino acids

Chemical FormulaC566H895N157O150S5

DescriptionStandard

        HQPMLLLAITEFVANSAAFTYFTAGALQRNISSDMLPRRFPLKLKTKSMGLFSPQLQERYPDHPMELHLSARQQPRLSCRPNALHGALFISAEAFVVLPNATRVPAFLLNI
    

Molecular Weight12459.45 Da

Isoelectric Point (pI)10.16

Net Charge (pH 7.0)5.11

Net Charge (pH 7.4) 4.67

Charge Density (pH 7.0) 0.0460

GRAVY Index0.05

Hydrophobic Moment 0.59

Boman Index0.09

Instability Index53.18

Aliphatic Index 95.95

Aromaticity 0.0901

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4865.64

LogP -42.11

H-bond Donors 166.0

H-bond Acceptors 164.0

Rotatable Bonds 399.0

Heavy Atoms 878.0

Ring Count 24.0

Amide Bonds 121.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0268864 VERIFIED: NO

Provenance & Taxonomy

OrganismAlca torda [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria