Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Standard StatusStandard

Sequence Length70 amino acids

Chemical FormulaC357H581N103O99S8

DescriptionStandard

        MRVLLSVLAVLTLLSIVPLARSFLEGQECSSEHRHCRMKCDTTEYAIKYCEDWTICCGAKHREAKKKRLW
    

Molecular Weight8156.58 Da

Isoelectric Point (pI)8.85

Net Charge (pH 7.0)3.71

Net Charge (pH 7.4) 3.24

Charge Density (pH 7.0) 0.0530

GRAVY Index-0.14

Hydrophobic Moment 0.57

Boman Index-0.07

Instability Index45.76

Aliphatic Index 90.57

Aromaticity 0.0714

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3271.59

LogP -27.29

H-bond Donors 125.0

H-bond Acceptors 114.0

Rotatable Bonds 276.0

Heavy Atoms 567.0

Ring Count 11.0

Amide Bonds 70.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0142995 VERIFIED: NO

Provenance & Taxonomy

OrganismPeromyscus maniculatus bairdii [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized peptide with linear backbone [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin

MethodQualitative functional evidence