Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length430 amino acids

Chemical FormulaC2226H3562N568O626S12

DescriptionStandard

        MKLLEQELRTRIFPDEIGTEKYFFGKVDYTVSRIQIMSTSIYNSSVVLIPGNSIGLLIKNISVTVTTHWTLNNWLIDYQGEVEISILGLSITTNMIVAQNNRGDFLVSVENCQLTTGNIEVQLNSEGRWFYNAFVQRLEKVIRTRLENQLCLNVILRIQKETKVLKGLKGVFQINPFIQVKYSLIKPPEVFKSYVDLDFKVSVYFSSNHTESPFVAAPITLPEKNNYMLFGGISESLLNSITLTYYTTRVSKITFLEEHSSNFNLTTDTLSRVIPQVIQHYAKSHPVRMKLMVTAAPVLRLQNNSFTIEIPCFVVVSALLSNSMIKPIFAMNASIGLKAKAVIAKQKLIVLLQLQRLYLSLTYSSIGSFQVQRLKNFLSYSLQNTVIPPIAAALKRGLQLPTMAKLVFSEAVTEVNKGYILISTDLNYKY
    

Molecular Weight48682.30 Da

Isoelectric Point (pI)9.49

Net Charge (pH 7.0)13.93

Net Charge (pH 7.4) 13.31

Charge Density (pH 7.0) 0.0324

GRAVY Index0.16

Hydrophobic Moment 0.81

Boman Index0.13

Instability Index32.34

Aliphatic Index 112.35

Aromaticity 0.0977

Extinction Coeff. Reduced 43320.00

Extinction Coeff. Oxidized 43445.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0321118 VERIFIED: NO

Provenance & Taxonomy

OrganismPantherophis guttatus (Corn snake) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria