Peptide Database

Peptide NameProbable insulin-like peptide 6

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological modulation

Standard StatusStandard

Sequence Length74 amino acids

Chemical FormulaC350H573N103O109S8

DescriptionStandard

        SPLAPTEYEQRRMMCSTGLSDVIQKICVSGTVALGDVFPNSFGKRRKRDLQNVTDLCCKSGGCTYRELLQYCKG
    

Molecular Weight8224.44 Da

Isoelectric Point (pI)8.85

Net Charge (pH 7.0)3.41

Net Charge (pH 7.4) 3.09

Charge Density (pH 7.0) 0.0460

GRAVY Index-0.37

Hydrophobic Moment 0.58

Boman Index-0.11

Instability Index52.77

Aliphatic Index 69.73

Aromaticity 0.0676

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3465.61

LogP -40.73

H-bond Donors 128.0

H-bond Acceptors 121.0

Rotatable Bonds 277.0

Heavy Atoms 570.0

Ring Count 8.0

Amide Bonds 79.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0400022 VERIFIED: YES

Provenance & Taxonomy

OrganismDrosophila melanogaster [Animal]

FamilyProbable insulin-like peptide

Tax ID7227

Structure & Mods

Configlinear peptide with reported disulfide constraint [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide15-58; 27-72; 57-63

Bio-Activity Profile

Function

Hormone Endocrine Receptor modulation

Half-LifeMammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour