Peptide Database

Peptide NameCircularin A uberolysin family circular bacteriocin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length62 amino acids

Chemical FormulaC286H485N75O82S5

DescriptionStandard

        MLKISERTAMGAMTVILATSDILTAISLCAAVLGGTGLITAGMVQTAKYLAKNKGKKYAAQW
    

Molecular Weight6446.69 Da

Isoelectric Point (pI)9.81

Net Charge (pH 7.0)4.49

Net Charge (pH 7.4) 4.24

Charge Density (pH 7.0) 0.0724

GRAVY Index0.53

Hydrophobic Moment 0.49

Boman Index0.24

Instability Index18.74

Aliphatic Index 107.26

Aromaticity 0.0484

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2518.86

LogP -23.51

H-bond Donors 91.0

H-bond Acceptors 92.0

Rotatable Bonds 220.0

Heavy Atoms 448.0

Ring Count 4.0

Amide Bonds 64.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0270188 VERIFIED: NO

Provenance & Taxonomy

OrganismBacillus cereus [Bacterium]

FamilyCircular bacteriocin

Structure & Mods

Configcyclic peptide topology reported [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriocin Non-hemolytic Non-ribosomal