Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length157 amino acids

Chemical FormulaC794H1201N181O238S7

DescriptionStandard

        QGIVYPAGNYTGSPYVAAPFTIPHQSDSMLYLAFSEYFFRTSSFAYYTAGAFNITIAEETCSYFNISTEIFGSIIPEVAKYSVTPYPVMLKLTATEIPIISLEQDSFTVEIQGSMEVFAVLPDSTTQLLFTMNMAANTSIALNIFDQKLVGSLCLNR
    

Molecular Weight17314.55 Da

Isoelectric Point (pI)4.28

Net Charge (pH 7.0)-8.16

Net Charge (pH 7.4) -8.48

Charge Density (pH 7.0) -0.0519

GRAVY Index0.33

Hydrophobic Moment 0.55

Boman Index0.26

Instability Index44.10

Aliphatic Index 90.13

Aromaticity 0.1401

Extinction Coeff. Reduced 14900.00

Extinction Coeff. Oxidized 15025.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6628.85

LogP -59.72

H-bond Donors 228.0

H-bond Acceptors 238.0

Rotatable Bonds 546.0

Heavy Atoms 1220.0

Ring Count 32.0

Amide Bonds 169.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0140787 VERIFIED: NO

Provenance & Taxonomy

OrganismChionis minor [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria