Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length304 amino acids

Chemical FormulaC1516H2363N397O435S10

DescriptionStandard

        LDLQSFSLPYSRISLAPNVGLQVSISNAFAEVDGDWRVKLLFIRDHGSFNLNVESVYLRVNLKLGNDASGKPTVDTSSCSVYISNVRVHFSGKFGWLYNLFYNVVESRFRNILESKVCETVASSVRNDLQPYLRTLPVAARIDAIAGIDYSLVAPPTATAQSLDAELKGEFFSMVRRSAVPFTPLPMALPPDHNRMVYFGASSFFFNTAGFAYHTAGALVFEITDSMVISSRNGGLCRYPNLLPATLQLEKMYPDMPMKIRLSSSSAPSLNIRPEGLSLQPVVDVQAYAILPNSSLAPLFLLGL
    

Molecular Weight33431.03 Da

Isoelectric Point (pI)7.87

Net Charge (pH 7.0)1.10

Net Charge (pH 7.4) 0.60

Charge Density (pH 7.0) 0.0036

GRAVY Index0.15

Hydrophobic Moment 0.60

Boman Index0.13

Instability Index51.63

Aliphatic Index 98.45

Aromaticity 0.1053

Extinction Coeff. Reduced 28880.00

Extinction Coeff. Oxidized 29005.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0422333 VERIFIED: NO

Provenance & Taxonomy

OrganismCeuthmochares aereus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria