Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length470 amino acids

Chemical FormulaC2364H3647N605O671S16

DescriptionStandard

        MLSLLILLLNLTNHAFGQNPAIKAILSNKGLQYGSHIGADWMQEKIGSVIIPDVRGGVDIGIGTVHYVLDGISVSGCDVPEPSVEFYEGVGLKAVISGLSISMSGNWHTRFGIITDGGSFDLAVFNVDVTSVVQIGSDQSGHISISSENCDASVGEASINFHGGASLIFQPFVSLFHHRIKAIIEERICPLVEEHVTDLERHLSEMQGIAVGRTKKENRLHKYYFYQYCGAHGVVFFTTVSFKVNSALVLDVPLTNSPLVDSISLGLDLKGEFYSVQSHTDPPFKAEPFNLPEDKGHMLSLGLSEFTVNSASYAYFSAGLLQAQINDSMIPKTSPFRLNTTSFGPLIPQLPKLFPNMLMELQVYARNVPIFSFQADKVTMEFPGAVKAFAIQPIHVHIDHIYTHCQTTLHHGIYLLTYKTIVCKPNDWTAEIVTLNYWFLFVAAKLEEGIVLPTMHHIHLVNPALKIQQV
    

Molecular Weight51791.93 Da

Isoelectric Point (pI)5.93

Net Charge (pH 7.0)-11.50

Net Charge (pH 7.4) -13.07

Charge Density (pH 7.0) -0.0245

GRAVY Index0.18

Hydrophobic Moment 0.62

Boman Index0.20

Instability Index34.58

Aliphatic Index 101.79

Aromaticity 0.0979

Extinction Coeff. Reduced 44350.00

Extinction Coeff. Oxidized 44725.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0160393 VERIFIED: NO

Provenance & Taxonomy

OrganismOncorhynchus mykiss [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria

MethodQualitative functional evidence