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MYP_000848
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Basic Information
PMM-5 (PMM analog)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
13 amino acids
C63H116N16O17
Standard
Sequence
KIASIGKEVLKAL
Physicochemical Analysis
1369.69 Da
9.70
1.76
1.55
0.1354
0.62
0.65
0.17
-10.36
157.69
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
548.11
-3.03
19.0
19.0
50.0
96.0
0.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0054853 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Gram-negative bacterium: Escherichia coli
100 μM
MIC
PMID18375018 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18375018/
RECORD: Rec_0079745 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli
100 μM
MIC
PMID18375018 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18375018/
RECORD: Rec_0181886 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Gram-positive bacterium: Bacillus subtilis
100 μM
MIC
PMID18375018 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18375018/
RECORD: Rec_0277512 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Rat RBC
100 μM
IC50
PMID18375018 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18375018/
RECORD: Rec_0320874 VERIFIED: YES
Provenance & Taxonomy
Polistes major major [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
Rat erythrocytes
100 μM
IC50
PaperCerovský V, Slaninová J, Fučík V, et al. New potent antimicrobial peptides from the venom of Polistinae wasps and their analogs. Peptides. 2008 Jun;29(6):992-1003. doi:10.1016/j.peptides.2008.02.007. PMID18375018 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18375018/
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