Peptide Database

Peptide NameUnnamed

Function Ontology

Enzyme modulation ▸ Enzyme inhibition ▸ DPP-IV inhibition ▸ DPP-IV inhibitory

Metabolic ▸ Glucose metabolism ▸ Antidiabetic

Standard StatusStandard

Sequence Length9 amino acids

Chemical FormulaC44H70N10O15S

DescriptionStandard

        MPPVDPNIE
    

Molecular Weight1011.15 Da

Isoelectric Point (pI)4.08

Net Charge (pH 7.0)-2.49

Net Charge (pH 7.4) -2.71

Charge Density (pH 7.0) -0.2767

GRAVY Index-0.52

Hydrophobic Moment 0.29

Boman Index0.12

Instability Index181.46

Aliphatic Index 75.56

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 387.44

LogP -2.53

H-bond Donors 10.0

H-bond Acceptors 14.0

Rotatable Bonds 27.0

Heavy Atoms 70.0

Ring Count 3.0

Amide Bonds 9.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0314544 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antidiabetic DPP-IV inhibitory

TargetDipeptidyl peptidase IV

PaperFaust J., Fuchs P., Wrenger S., Reinhold D., St?ckel-Maschek A., K?hne T., Ansorge S., Neubert K.. Dipeptidyl peptidase IV inhibitors with the N-terminal MXP sequence: Structure-activity-relationships. Adv. Exp. Med. Biol., 524, 175-179. PMID12675237 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12675237/