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MYP_000843
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Basic Information
Unnamed
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiparasitic ▸ Antiprotozoal ▸ Anti-Trypanosoma
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Antiviral
Antiviral ▸ Anti-Herpesvirus ▸ Anti-HSV
Antiviral ▸ Anti-HIV
Cardiovascular
Delivery / Targeting ▸ Barrier transport ▸ Blood-brain barrier shuttle ▸ Blood-Brain Barrier
Delivery / Targeting ▸ Drug delivery vehicle
Hormonal / Endocrine ▸ Hormone peptide
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Metabolic ▸ Appetite and feeding regulation ▸ Feeding regulator
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Analgesic
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide precursor
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide signaling
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Standard
13 amino acids
C75H106N20O19S
Standard
Sequence
SYSMEHFRWGKPV
Physicochemical Analysis
1623.83 Da
8.33
0.55
0.29
0.0422
-0.92
0.38
-0.07
34.02
22.31
0.2308
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
634.11
-4.11
23.0
22.0
49.0
115.0
6.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0052772 VERIFIED: YES
Provenance & Taxonomy
Pelophylax ridibundus [Animal]
POMC
8406
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hormone precursor Neuropeptide precursor
PMID19118555 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19118555/
RECORD: Rec_0054045 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 0.0%, T 38.5%, C 61.5% [Linear]
canonical L-amino-acid peptide [L]
Acetylation
None
Bio-Activity Profile
Drug Delivery Vehicle Blood-Brain Barrier
PaperBrainpeps: the blood-brain barrier peptide database PMID22205159 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22205159/
RECORD: Rec_0064223 VERIFIED: YES
Provenance & Taxonomy
Macaca nemestrina [Animal]
Melanocyte-stimulating hormone
9545
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Bio-Activity Profile
Hormone Endocrine Neuropeptide Neuromodulator
Mammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Melanocyte-stimulating hormone alpha (Macaca nemestrina): PMID 13760276 PMID13760276 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/13760276/
RECORD: Rec_0065029 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
alpha-Melanocyte-stimulating hormone
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiparasitic Antitrypanosomal
Trypanosoma brucei brucei AnTat 1.1 (blood stage form)
8.9±1.3 μM
LD50; MTT assay
PaperNeuropeptides kill African trypanosomes by targeting intracellular compartments and inducing autophagic-like cell death PMID19057622 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19057622/
RECORD: Rec_0065756 VERIFIED: YES
Provenance & Taxonomy
Neovison vison [Animal]
POMC
452646
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Bio-Activity Profile
Hormone precursor Neuropeptide precursor
PMID2854538 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2854538/
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