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MYP_000843
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Basic Information
Unnamed
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiparasitic ▸ Antiprotozoal ▸ Anti-Trypanosoma
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Antiviral
Antiviral ▸ Anti-Herpesvirus ▸ Anti-HSV
Antiviral ▸ Anti-HIV
Cardiovascular
Delivery / Targeting ▸ Barrier transport ▸ Blood-brain barrier shuttle ▸ Blood-Brain Barrier
Delivery / Targeting ▸ Drug delivery vehicle
Hormonal / Endocrine ▸ Hormone peptide
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Metabolic ▸ Appetite and feeding regulation ▸ Feeding regulator
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Analgesic
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide precursor
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide signaling
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Standard
13 amino acids
C75H106N20O19S
Standard
Sequence
SYSMEHFRWGKPV
Physicochemical Analysis
1623.83 Da
8.33
0.55
0.29
0.0422
-0.92
0.38
-0.07
34.02
22.31
0.2308
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
634.11
-4.11
23.0
22.0
49.0
115.0
6.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0296365 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Melanocortin (α-MSH)
9606.0
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antiviral Anti-HIV Anti-HSV
Herpesvirus, HIV
PaperAlpha-melanocyte-stimulating hormone peptides inhibit HIV-1 expression in chronically infected promonocytic U1 cells and in acutely infected monocytes; Patent: Treatment Of Ophthalmic Infections Using Antimicrobial Peptides PMID11073109 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11073109/ PatentUS 7244710
RECORD: Rec_0296950 VERIFIED: NO
Provenance & Taxonomy
Rattus norvegicus [Animal]
Melanocyte-stimulating hormone
10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Bio-Activity Profile
Hormone Endocrine Neuropeptide Neuromodulator Cardiovascular Metabolic regulation Physiological regulation Receptor modulation Feeding regulator
Mammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour
RECORD: Rec_0297768 VERIFIED: YES
Provenance & Taxonomy
Acipenser transmontanus [Animal]
POMC
7904
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hormone precursor Neuropeptide precursor
PMID13929167 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/13929167/
RECORD: Rec_0301349 VERIFIED: YES
Provenance & Taxonomy
Balaenoptera borealis [Animal]
Melanocyte-stimulating hormone
9768
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Bio-Activity Profile
Hormone Endocrine
Mammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Melanocyte-stimulating hormone alpha (Balaenoptera borealis): PMID 201308 PMID201308 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/201308/
RECORD: Rec_0340934 VERIFIED: YES
Provenance & Taxonomy
Sparus aurata [Animal]
Opioid
8175
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Opioid Analgesic Neuromodulator
PMID10927632 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10927632/
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