Peptide Database

Peptide NameProthyroliberin

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length236 amino acids

Chemical FormulaC1202H1889N367O380S7

DescriptionStandard

        FPPELSENMGRSSLDDILQRSGSHMLQSVLKKVEKKEEMNKELNMPLPQWLSKRQHPGKRYISDPEKRQHPGKRDVEEKASFGDIQKRQHLGKTEVEGYLVNYLELKKRQHPGRRSLWDQSTDISSSQLTYLNELSKRQHPGRRYLMYKHQHPSKRGWNDELDLSDQNWEKHQQFGNRDRDSDSPDYTGPCDLQQSAICNKDSLLLDLAEKFSKEGVEEKHQHPGRRSAWENETEE
    

Molecular Weight27785.54 Da

Isoelectric Point (pI)7.33

Net Charge (pH 7.0)0.76

Net Charge (pH 7.4) -0.13

Charge Density (pH 7.0) 0.0032

GRAVY Index-1.40

Hydrophobic Moment 0.67

Boman Index-0.33

Instability Index74.31

Aliphatic Index 56.99

Aromaticity 0.0678

Extinction Coeff. Reduced 37930.00

Extinction Coeff. Oxidized 38055.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0083436 VERIFIED: NO

Provenance & Taxonomy

OrganismGallus gallus [Animal]

FamilyTRH

Tax ID9031

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsGln55 Pyroglutamylation; Pro57 Amidation; Gln69 Pyroglutamylation; Pro71 Amidation; Gln89 Pyroglutamylation; Leu91 Amidation; Gln110 Pyroglutamylation; Pro112 Amidation; Gln139 Pyroglutamylation; Pro141 Amidation; Gln222 Pyroglutamylation; Pro224 Amidation

Bio-Activity Profile

Function

Hormone Neuropeptide