Peptide Database

Peptide NameInterleukin-12 subunit beta

Function Ontology

Immunology ▸ Immune modulation ▸ Cytokine modulation

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity

Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity

Standard StatusStandard

Sequence Length197 amino acids

Chemical FormulaC989H1592N264O301S17

DescriptionStandard

        RNLPVATPDPGMFPCLHHSQNLLRAVSNMLQKARQTLEFYPCTSEEIDHEDITKDKTSTVEACLPLELTKNESCLNSRETSFITNGSCLASRKTSFMMALCLSSIYEDLKMYQVEFKTMNAKLLMDPKRQIFLDQNMLAVIDELMQALNFNSETVPQKSSLEEPDFYKTKIKLCILLHAFRIRAVTIDRVMSYLNAS
    

Molecular Weight22541.91 Da

Isoelectric Point (pI)6.12

Net Charge (pH 7.0)-1.93

Net Charge (pH 7.4) -2.49

Charge Density (pH 7.0) -0.0098

GRAVY Index-0.22

Hydrophobic Moment 0.73

Boman Index-0.02

Instability Index50.78

Aliphatic Index 87.16

Aromaticity 0.0711

Extinction Coeff. Reduced 7450.00

Extinction Coeff. Oxidized 7825.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 9140.08

LogP -117.39

H-bond Donors 319.0

H-bond Acceptors 320.0

Rotatable Bonds 700.0

Heavy Atoms 1571.0

Ring Count 27.0

Amide Bonds 215.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0177644 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyIL-6 superfamily

Tax ID9606; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide42-174; 63-101

Bio-Activity Profile

Function

Cytokine Growth factor IL-6 superfamily Host defense