Peptide Database

Peptide NameHepcidin antimicrobial peptide 1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length95 amino acids

Chemical FormulaC476H743N143O137S9

DescriptionStandard

        MKAFSIAAAVTLVLAFVCFLEISAVPFTTVQELEEARGRDNTPAETHQETPVHSQMTLNHVRHRRWSHIHLCRWCRNCCDSDAWVYCCRTTKTSK
    

Molecular Weight10949.45 Da

Isoelectric Point (pI)8.23

Net Charge (pH 7.0)1.97

Net Charge (pH 7.4) 1.33

Charge Density (pH 7.0) 0.0207

GRAVY Index-0.23

Hydrophobic Moment 0.69

Boman Index-0.05

Instability Index55.96

Aliphatic Index 70.84

Aromaticity 0.0842

Extinction Coeff. Reduced 17990.00

Extinction Coeff. Oxidized 18365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4503.21

LogP -46.85

H-bond Donors 168.0

H-bond Acceptors 154.0

Rotatable Bonds 352.0

Heavy Atoms 765.0

Ring Count 20.0

Amide Bonds 100.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0147665 VERIFIED: YES

Provenance & Taxonomy

OrganismSolea senegalensis [Animal]

FamilyHepcidin

Tax ID28829

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal

RECORD: Rec_0322716 VERIFIED: NO