Peptide Database

Peptide NameGrowth/differentiation factor 5

Function Ontology

Immunology ▸ Immune modulation ▸ Cytokine modulation

Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity

Standard StatusStandard

Sequence Length120 amino acids

Chemical FormulaC595H934N166O176S11

DescriptionStandard

        APLATRQGKRPSKNLKARCSRKALHVNFKDMGWDDWIIAPLEYEAFHCEGLCEFPLRSHLEPTNHAVIQTLMNSMDPESTPPTCCVPTRLSPISILFIDSANNVVYKQYEDMVVESCGCR
    

Molecular Weight13581.50 Da

Isoelectric Point (pI)6.46

Net Charge (pH 7.0)-0.90

Net Charge (pH 7.4) -1.43

Charge Density (pH 7.0) -0.0075

GRAVY Index-0.32

Hydrophobic Moment 0.76

Boman Index-0.02

Instability Index44.49

Aliphatic Index 75.58

Aromaticity 0.0750

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5448.19

LogP -53.54

H-bond Donors 192.0

H-bond Acceptors 190.0

Rotatable Bonds 437.0

Heavy Atoms 948.0

Ring Count 25.0

Amide Bonds 128.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0096687 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyTGF-beta family

Tax ID9606; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide19-85; 48-117; 52-119

Bio-Activity Profile

Function

Cytokine Growth factor TGF-beta family Growth factor signaling