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MYP_000715
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Basic Information
Ala46 substitution mutant of pAntp (43-58)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
16 amino acids
C101H161N33O20S
Standard
Sequence
RQIAIWFQNRRMKWKK
Physicochemical Analysis
2189.63 Da
12.00
5.76
5.55
0.3598
-1.38
0.22
-0.48
57.21
55.00
0.1875
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
924.43
-5.19
34.0
27.0
76.0
155.0
5.0
18.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0031037 VERIFIED: YES
Provenance & Taxonomy
Drosophila melanogaster [Animal]
Penetratin
7227
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Biotinylation
Amidation
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
PaperStructure-activity relationship of truncated and substituted analogues of the intracellular delivery vector Penetratin PMID10784032 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10784032/
RECORD: Rec_0110543 VERIFIED: YES
Provenance & Taxonomy
Protein derived [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Biotinylation (Labeled with Biotinyl-beta-Alanine)
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID10784032 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10784032/
RECORD: Rec_0246029 VERIFIED: YES
Provenance & Taxonomy
Drosophila melanogaster [Animal]
Penetratin
7227
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Biotinylation
Amidation
N-term detail: Labeled with Biotinyl-bAla
Bio-Activity Profile
Cell-penetrating peptide
HaCat/ A549 cells
Cellular uptake assay
PMID10784032 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10784032/
RECORD: Rec_0304836 VERIFIED: YES
Provenance & Taxonomy
Protein derived [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Biotinylation (Labeled with Biotinyl-beta-Alanine)
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PMID10784032 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10784032/
RECORD: Rec_0378519 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Labeled with Biotinyl-bAla
Amidation
Bio-Activity Profile
Drug Delivery Vehicle Cell-penetrating peptide
PaperCPPsite: a curated database of cell penetrating peptides PMID22403286 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22403286/
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