Peptide Database

Peptide NameEnkephalin analog

Function Ontology

Neurological / Signaling ▸ Analgesic/opioid activity ▸ Analgesic

Standard StatusStandard

Sequence Length6 amino acids

Chemical FormulaC30H46N8O9S

DescriptionStandard

        PCLPHE
    

Molecular Weight694.80 Da

Isoelectric Point (pI)5.48

Net Charge (pH 7.0)-0.96

Net Charge (pH 7.4) -1.08

Charge Density (pH 7.0) -0.1594

GRAVY Index-0.60

Hydrophobic Moment 0.18

Boman Index0.07

Instability Index59.97

Aliphatic Index 65.00

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 252.02

LogP -1.44

H-bond Donors 9.0

H-bond Acceptors 10.0

Rotatable Bonds 18.0

Heavy Atoms 48.0

Ring Count 3.0

Amide Bonds 5.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0023561 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyEnkephalin

Structure & Mods

Configlinear peptide [Linear]

Chiralitymixed L/D amino-acid peptide [Mixed]

N-TermNone

C-TermHydroxylation

Other ModsPara chlorination of amino group of phenylalanine

Bio-Activity Profile

Function

Analgesic

MethodHPLC , reverse phase HPLC, Partition coefficient

Half-LifeMouse brain proteases, in vitro; >18000 s