Peptide Database

Peptide NamePotassium channel toxin alpha-KTx 2.18

Function Ontology

Membrane / Ion-channel modulation ▸ Ion channel modulation

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length39 amino acids

Chemical FormulaC179H301N55O51S6

DescriptionStandard

        TTINVKCTSPKQCLPPCKEIYGRHAGAKCINGKCHCSKI
    

Molecular Weight4232.03 Da

Isoelectric Point (pI)9.27

Net Charge (pH 7.0)5.51

Net Charge (pH 7.4) 5.12

Charge Density (pH 7.0) 0.1413

GRAVY Index-0.38

Hydrophobic Moment 0.43

Boman Index-0.08

Instability Index51.32

Aliphatic Index 62.56

Aromaticity 0.0256

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1706.08

LogP -20.34

H-bond Donors 64.0

H-bond Acceptors 65.0

Rotatable Bonds 140.0

Heavy Atoms 291.0

Ring Count 6.0

Amide Bonds 41.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0266855 VERIFIED: NO

Provenance & Taxonomy

OrganismCentruroides limpidus [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Toxin Ion channel blocker

TargetKv1.3/KCNA3