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MYP_000644
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Basic Information
W17-6K
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
17 amino acids
C93H144N26O18
Standard
Sequence
KKKKKKAAWAAWAAWAA
Physicochemical Analysis
1914.30 Da
10.70
5.75
5.54
0.3385
-0.69
0.24
-0.09
-17.11
47.06
0.1765
16500.00
16500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
732.41
-2.74
27.0
24.0
63.0
137.0
6.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0000296 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli UB1005
1 μM
MIC
PMID12384369 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12384369/
RECORD: Rec_0046755 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis ATCC 6633
4 μM
MIC
PMID12384369 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12384369/
RECORD: Rec_0092316 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 41.2%, E 0.0%, T 47.1%, C 11.8% [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Toxic Antimicrobial Hemolytic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
RECORD: Rec_0110404 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC 25923
32 μM
MIC
PMID12384369 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12384369/
RECORD: Rec_0130510 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
Human erythrocytes
200 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/12384369/ PMID12384369 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12384369/
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