Peptide Database

Peptide NamePyocin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length522 amino acids

Chemical FormulaC2473H3907N711O775S14

DescriptionStandard

        MAKGYILHMYDPTTCGGRILEGAPNRRTNGTPVARMGDKISCGKDNKTYQIIGGISWIKTEGRLVAGSLDSFSSCPCNAKIIPQITVQTYESRSESKENSPVAATPPSTVVSSNSSALAGSATLLPVPVFAKSRERGAGNTDAGKQQEPHTNFAEMGLFRAAPAADAVIDSDAPQHAQTAKKKPKAPENIPKPKKRSALYKSFNGNHEEVEYQAAVAAAASATRAQAATAGVNVLEQIAGRFTTYGTWAATGAEVAAGGIGISVAGFLVGMMPGRLNDDEQDFIDRMRLAQMSEAPTRVRYTWENDSNGNPVPHGWHTPPGKDMVRVRKMQWDSTRQAYTFTAEEENLVTIIWTPDSSGVNTPSNTGDQSQPRLPGTILVNPLPDGTQISSTTTPAPDEKNFADYILIVPVSDIPPIYIYLSNVREGLPEKDHSYHPAPKTEEIVGISGIQKAKKKTPKQGGGGLRERWIDAKGKRIYEWDSQHGELEEYRASDGEHLGSVDYKTGNQLKPAVKGRSIKRYL
    

Molecular Weight56447.69 Da

Isoelectric Point (pI)8.60

Net Charge (pH 7.0)4.40

Net Charge (pH 7.4) 3.47

Charge Density (pH 7.0) 0.0084

GRAVY Index-0.57

Hydrophobic Moment 0.66

Boman Index-0.05

Instability Index40.38

Aliphatic Index 68.10

Aromaticity 0.0670

Extinction Coeff. Reduced 69330.00

Extinction Coeff. Oxidized 69580.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0130446 VERIFIED: YES

Provenance & Taxonomy

OrganismEnterobacter cloacae [Bacterium]

FamilyPyocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

TargetEscherichia coli (Gram-negative)