Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length526 amino acids

Chemical FormulaC2583H4082N698O729S19

DescriptionStandard

        MGWDGIGVEGKGNPERVAGGGGTGGPPPAPAVPPAPGRGSWNTPGTRGPACACVCTCVHVCGCARTCVLCGGSPLFQSTQAGLDYAHQHGIAILEKELAQLKLPDISGDTRVLRVGKVHYELSRLRLRDFHLPYSRITPVSNVGLQVSISNAFAELDGDWRVKLFFVRDHGSFNLKVENVYIKISLRLGSDTTGKPTISTSDCSASISKVRVLFSGKLGWLYNLFHKTIESRLRKILEVKVCDSVAKSVNKELQTYIQTLPVTAKIDNKTGIDYSLVAPPRATAQSLDADLKGEFYSLAKRFTVPFSPLPLAFPSDHERMVYFGASSYFFNTAGIAYQKAGALVFEITEAMIPKEAGFRLDTSVFSAFIPQLEEMYPNMPMKFRLSAPTAPFLTIGPGGISFQPIVDAQAYAILPNSSLVPLFLLSLTGNVSAVINERSGRIVGSLDVGRIRISLKDSAVGTFQVRMMQSIMNVFTSSTLLPRVNARLHEGFPLPLLDRIQLSNVLVKFHQNFLLLGADVHFQPLV
    

Molecular Weight57187.52 Da

Isoelectric Point (pI)9.19

Net Charge (pH 7.0)12.40

Net Charge (pH 7.4) 11.38

Charge Density (pH 7.0) 0.0236

GRAVY Index0.09

Hydrophobic Moment 0.68

Boman Index0.12

Instability Index34.60

Aliphatic Index 94.89

Aromaticity 0.0875

Extinction Coeff. Reduced 41370.00

Extinction Coeff. Oxidized 41995.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0394494 VERIFIED: NO

Provenance & Taxonomy

OrganismFicedula albicollis (Collared flycatcher) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria