Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length44 amino acids

Chemical FormulaC217H351N57O69S4

DescriptionStandard

        MAKQQMNLVEIEAMNSLQELTLEELDNVLGAGSGIIHFMQTKQW
    

Molecular Weight4990.71 Da

Isoelectric Point (pI)4.41

Net Charge (pH 7.0)-4.40

Net Charge (pH 7.4) -4.68

Charge Density (pH 7.0) -0.1000

GRAVY Index-0.10

Hydrophobic Moment 0.40

Boman Index0.12

Instability Index56.13

Aliphatic Index 99.77

Aromaticity 0.0455

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2060.57

LogP -18.37

H-bond Donors 67.0

H-bond Acceptors 70.0

Rotatable Bonds 175.0

Heavy Atoms 347.0

Ring Count 4.0

Amide Bonds 51.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0164499 VERIFIED: YES

Provenance & Taxonomy

OrganismStreptococcus mitis [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic

TargetGram-positive bacteria