Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length456 amino acids

Chemical FormulaC2300H3616N622O643S10

DescriptionStandard

        TNPGFVVRITQAGLDYAHQHGITILEKELAQLKLPDISGDSRVLRVGKVRYQLSRLHLSSFHLPYSRISPVPNVGLQVSISNAFAELDGDWRVKVLFMRDHGSFNLKVENVYIKVSLRLGSDASGKPTVSTSDCSTRISKVRVHFSGRLGWLYNLFHNAIESRFKKMLETKVCDSVAKSVHNDLQRYLQTLPVTARIDARAGIDYSLVAPPSATAQSLDAALKGEFYSLAHRSTVPFSPLPLSFPSDHDHMVYFGISSYFFNTAGFAYHTAGALVFEITDAMIPKDVDFHLNTTTFSAFIPQLEHMYPDMPMKLKLSTPSAPFLNIGPEGISLRPVVDVQAYAILPNSSLAPLFLLSLVRNVSAVIDVRSGHIVGSLDVGRIRLSLKDSVVGTFPVRLLQSIMNIFASEILLPRLNARLETGFPLPLPDRIQLSNTLVRFHQNFLLLGADVHFQPQ
    

Molecular Weight50589.75 Da

Isoelectric Point (pI)9.27

Net Charge (pH 7.0)7.89

Net Charge (pH 7.4) 6.73

Charge Density (pH 7.0) 0.0173

GRAVY Index0.08

Hydrophobic Moment 0.71

Boman Index0.11

Instability Index38.23

Aliphatic Index 102.59

Aromaticity 0.0921

Extinction Coeff. Reduced 30370.00

Extinction Coeff. Oxidized 30495.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0158561 VERIFIED: NO

Provenance & Taxonomy

OrganismSakesphorus luctuosus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria