Peptide Database

Peptide Name[R17D]GexIVA[1,4]

Function Ontology

Neurological / Signaling ▸ Analgesic/opioid activity ▸ Analgesic

Standard StatusStandard

Sequence Length28 amino acids

Chemical FormulaC137H224N52O43S4

DescriptionStandard

        TCRSSGRYCRSPYDRRDRYCRRITDACV
    

Molecular Weight3415.83 Da

Isoelectric Point (pI)9.57

Net Charge (pH 7.0)4.36

Net Charge (pH 7.4) 4.10

Charge Density (pH 7.0) 0.1557

GRAVY Index-1.27

Hydrophobic Moment 0.79

Boman Index-0.64

Instability Index115.20

Aliphatic Index 27.86

Aromaticity 0.1071

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4720.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1609.17

LogP -21.82

H-bond Donors 67.0

H-bond Acceptors 52.0

Rotatable Bonds 110.0

Heavy Atoms 236.0

Ring Count 4.0

Amide Bonds 27.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0206077 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyConotoxin

Tax ID32630

Structure & Mods

Configdisulfide-constrained linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide2-27; 9-20

Bio-Activity Profile

Function

Analgesic

Targetα9α10 nicotinic acetylcholine receptor