Peptide Database

Peptide NamePyocin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length294 amino acids

Chemical FormulaC1418H2247N405O447S4

DescriptionStandard

        MTSVDLPVRGFITTDDDGRQSVNFVRTGVGGVSPSVPVFRPVRDELTGLDKITLPAVAGTPARTILINPVPTGPAAPAHTGNGSPGPKSPVHTGTGIRQADSIVVTTFPADVVQDLQDFILWQPDATEIGVEAIYVMVSKPYGETNARGKYSGREYNTNKAGGPIQNLDWKGASIDRAGVDKVKLHTGRFEQTPENQVMIDRLDKILKGELQPTDTDRRFYTHEIRELERYRNLGIKDGEVPHSVQEQKAVWNNTHTATLEDYRINEKEQALYTDGALQAAYEQELKDAMGGKK
    

Molecular Weight32248.72 Da

Isoelectric Point (pI)5.60

Net Charge (pH 7.0)-5.93

Net Charge (pH 7.4) -6.53

Charge Density (pH 7.0) -0.0202

GRAVY Index-0.57

Hydrophobic Moment 0.69

Boman Index-0.06

Instability Index31.37

Aliphatic Index 76.90

Aromaticity 0.0646

Extinction Coeff. Reduced 29910.00

Extinction Coeff. Oxidized 29910.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0091169 VERIFIED: YES

Provenance & Taxonomy

OrganismSerratia marcescens [Bacterium]

FamilyPyocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

TargetEscherichia coli (Gram-negative)