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MYP_000519
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Basic Information
Corticoliberin
Hormonal / Endocrine ▸ Hormone peptide
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Neurological / Signaling ▸ Neuropeptide activity ▸ Stress-related neuropeptide
Regulatory peptide ▸ Cell-cell communication
Standard
41 amino acids
C206H339N59O64S
Standard
Sequence
SQEPPISLDLTFHLLREVLEMTKADQLAQQAHNNRKLLDIA
Physicochemical Analysis
4698.32 Da
5.40
-2.36
-2.67
-0.0575
-0.39
0.65
-0.06
39.81
111.95
0.0244
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2006.20
-18.71
66.0
65.0
160.0
330.0
5.0
46.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0204831 VERIFIED: NO
Provenance & Taxonomy
Bos taurus [Animal]
Corticoliberin
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hormone Endocrine Neuropeptide Neuromodulator
-
Mammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour
PMID15771721 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15771721/
RECORD: Rec_0270633 VERIFIED: NO
Provenance & Taxonomy
Bos taurus [Animal]
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hormone
RECORD: Rec_0296096 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide
Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/
RECORD: Rec_0411183 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 78.0%, E 0.0%, T 2.4%, C 19.5% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Cell-Cell Communication
PaperNeuroPedia: neuropeptide database and spectral library PMID21821666 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21821666/