Peptide Database

Peptide NamePaLEAP-2

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length41 amino acids

Chemical FormulaC196H300N56O58S7

DescriptionStandard

        MTPLWRTMGTKPYGAYCQNNYECSTGICRGGHCMFSQAIKS
    

Molecular Weight4593.27 Da

Isoelectric Point (pI)8.86

Net Charge (pH 7.0)2.55

Net Charge (pH 7.4) 2.21

Charge Density (pH 7.0) 0.0621

GRAVY Index-0.43

Hydrophobic Moment 0.53

Boman Index0.01

Instability Index21.19

Aliphatic Index 33.41

Aromaticity 0.1220

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10220.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1842.01

LogP -21.68

H-bond Donors 69.0

H-bond Acceptors 69.0

Rotatable Bonds 146.0

Heavy Atoms 317.0

Ring Count 9.0

Amide Bonds 44.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0242589 VERIFIED: YES

Provenance & Taxonomy

OrganismSalmo trutta [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)