Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length302 amino acids

Chemical FormulaC1491H2341N389O440S13

DescriptionStandard

        MKCTAATCRAEMVSVLTLTLTLTLTLSPGTDAADPGFVVRLTQKGLDYARDEGMSVLQQQLAKIHLPDFSGSTHIKHMGTVKYSFDSMAVRSFQLPSSQISLVPGVGLKLTISGAFIQVDGQWKISYIHMWLVDLFQHNIEKDLRKAIEDQICPLVSESITTKLEPLLQTLPVTAKIDGVAAIDYSLTGTPLVMSEFVDVPLKGEFFNYGNRSAPPFSPPALSFPAEHSLMVYFGASEYLFNTAGYVYQMAGKLSFTITDDMVRGGGRLSGYPVPTRYSESHRGTQIRRSELTAGSRNVQYP
    

Molecular Weight33172.72 Da

Isoelectric Point (pI)6.65

Net Charge (pH 7.0)-0.89

Net Charge (pH 7.4) -1.58

Charge Density (pH 7.0) -0.0030

GRAVY Index-0.01

Hydrophobic Moment 0.74

Boman Index0.11

Instability Index45.73

Aliphatic Index 88.44

Aromaticity 0.0927

Extinction Coeff. Reduced 28880.00

Extinction Coeff. Oxidized 29005.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0327084 VERIFIED: NO

Provenance & Taxonomy

OrganismLeptobrachium leishanense [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria

MethodQualitative functional evidence