Peptide Database

Peptide NameBeta-defensin 1TB

Function Ontology

—

Standard StatusStandard

Sequence Length35 amino acids

Chemical FormulaC164H255N49O47S6

DescriptionStandard

        DHYRCVKKGGTCNFSPCPLFNRIEGTCYGGKAKCC
    

Molecular Weight3857.47 Da

Isoelectric Point (pI)8.89

Net Charge (pH 7.0)3.79

Net Charge (pH 7.4) 3.43

Charge Density (pH 7.0) 0.1082

GRAVY Index-0.48

Hydrophobic Moment 0.58

Boman Index-0.10

Instability Index33.55

Aliphatic Index 33.43

Aromaticity 0.1143

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1553.63

LogP -18.37

H-bond Donors 60.0

H-bond Acceptors 58.0

Rotatable Bonds 124.0

Heavy Atoms 266.0

Ring Count 7.0

Amide Bonds 36.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0025789 VERIFIED: YES

Provenance & Taxonomy

OrganismLipotes vexillifer [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)