Peptide Database

Peptide NameBrevicillin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Antiviral

Venom / Toxin ▸ General toxin ▸ Toxicity

Standard StatusStandard

Sequence Length24 amino acids

Chemical FormulaC106H165N27O39S5

DescriptionStandard

        SDSVVSDIICTTFCSVTWCQSNCC
    

Molecular Weight2601.93 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-2.59

Net Charge (pH 7.4) -2.87

Charge Density (pH 7.0) -0.1078

GRAVY Index0.66

Hydrophobic Moment 0.35

Boman Index0.21

Instability Index40.50

Aliphatic Index 68.75

Aromaticity 0.0833

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5750.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1071.03

LogP -15.58

H-bond Donors 43.0

H-bond Acceptors 42.0

Rotatable Bonds 80.0

Heavy Atoms 177.0

Ring Count 3.0

Amide Bonds 25.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0155421 VERIFIED: YES

Provenance & Taxonomy

OrganismBrevibacillus sp [Bacterium]

FamilyBacteriocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other Modsgenome mining and sequence alignment. Antimicrobial substance was extracted from cell free fermented broth using diaion HP20 resin and subsequently purified by HPLC. Sequence analysis: APD analysis reveals this sequence is most similar (41.38%) to Thuricin 4A-4 C=S: 21%; V=T: 13%. GRAVY: 0.66; M Wt: 2601.967; Mol formula: C106H167N26O39S5; molar extinction coeff: 5550. Chemical modification: not yet fully established

Bio-Activity Profile

Function

Antimicrobial Antifungal Antiviral

TargetStaphylococcus aureus MTCC 1430

Activity0.8 μg/mL

MethodMIC

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